Quite looking forward to this match.
Should be a good battle in the front-row - I'd give Wales a slight edge here, but I'm not overly familiar with Ken Owens. Wales will be happy to have Alun Wyn Jones back at lock, but I do feel they still miss some real 'grunt' in the second row (which Davies provides, and - somewhat surprisingly to me - Charteris provided during the RWC). I think Wales have a slight edge in this department too, though I do think Botha has been pretty solid for England thus far (I have seen very little of Parling though). Again I think Wales have a slight edge in the loose-forwards, particularly at the breakdown. I am interested to see how Ben Morgan goes for England though, as I've heard a lot about him.
I the halves again I see Wales having a slight edge. England will (hopefully) be getting better ball delivered by Dickson, and I do think Youngs could add something to the England attack with his sniping runs if he comes on with 15-20 mins to go (as he did versus Argentina in the RWC). I thought Priestland has been pretty quiet so far (is he injured somehow?), and I think his duel with Farrell will be interesting. Yet again I think Wales have a (slight) edge in the midfield, due to Barritt's inexperience (though he has been rock solid thus far) and the fact that Tuilagi is only just back from injury. Though I'm becoming more of a fan of Davies each time I see him I'm still not yet convinced about his defense, and he may struggle to contain Tuiagi, who can run some great angles at times (and at pace). I think it is pretty even out wide: I'd take North over Ashton on current form (though Ashton at his best is pretty handy), and Cuthbert v Strettle is an interesting matchup. Cuthbert was pretty average in the first match, but looked far more assured in the second match, while Strettle has been pretty solid thus far. Strettle has never really impressed me at international level - he has never looked that poor either - I just wonder whether he has that extra spark that is sometimes needed at the higher level. Both fullbacks are quality - Foden may have been a bit quite lately, but when on form he is very dangerous.
So, in conclusion, I think Wales have a slight edge in almost every area, with the only area they have a big advantage in is at the breakdown. I think England's home ground advantage almost negates this edge... almost. I'm picking Wales to win by 5-10.