I can't see anything but an England win, provided England turn up (unlike 2015). We're missing Henderson, McCarthy, SOB, O'Mahony, Fitzgerald, (probably) Payne, Dave Kearney and Bowe together with an out of form and undercooked Healy and Ross, a 35 yr old Reddan, an out of form Ryan, Zebo and Madigan as well as McFadden (needs no description).
The only area I see us competing and (hopefully) winning is the breakdown, provided England go with a Robshaw/Haskell/Vunipola back row. Ford is out of form so if we send Stander down his channel all day, he could get rattled.
Rumours are Earls has been running in the 13 channel in training. If Payne isn't fit and Schmidt puts Earls at 13, we will get steamrolled. He's an average to decent international wing and is a poor Champions Cup 13. Joseph will have a field day against Earls.
If Ireland get a fast start and put a decent score on the board early, I could see us sneaking the win. However, England seem to have too much power up front with electric backs in Joseph and Watson to cut us apart. I predict England by 7+, being generous to Ireland.
Ireland will line out something like this (provided Payne is injured):
1. McGrath
2. Best
3. Ross
4. Ryan
5. Toner
6. Stander
7. TOD
8. Heaslip
9. Murray
10. Sexton
11. Zebo
12. Henshaw
13. Earls
14. Trimble
15. Kearney