It's a real shame that PsdT is out, I'd like to say that we have plenty of cover at lock and that it won't hurt us that much, but in the end he is our form lock at the moment so their will be a small drop-off. He does seem to just be one of those players that is always injured glad we have Lood as back up.
As for our general chances against the Irish it's just really hard to say, especially as someone who usually doesn't watch much six nations, no doubt we won't be as strong a side as last year. We've lost a few stalwarts, we have a new coach, and a new quota system that may hamper us a little.
That said it's a very young squad the majority of the players are 25 or younger so there is plenty of hope for the future, not to mention the feeling that some of the form players in SA (the Lions lads) are finally getting a crack. I'm just really excited to see us play but not at all confident of a clean sweep (or even a series victory).
Edit: Not to mention there is no proof that we were even a better side than Ireland last year, they did smash us at the EoTY tour 2014.