I think the emphasis should be completely on attack. We know England can put out a good defensive back line, coached well by Andy Farrell. We know, as well, that unless England start converting chances and scoring tries they won't win against strong sides. I also don't think that Lancaster will be too conservative; everyone else will be watching the Lions, so he might as well use the opportunity. In the past he's shown he's not afraid of experimenting.
So, given the current EPS and Saxons, and expecting Cole, both Youngs brothers, Parling, Wood, Robshaw, Tuilagi, and Farrell going off with the Lions, I'd hope to see the following start against Argentina:
1. Corbisiero
2. Hartley (c) -- Old head. Might not get binned this time...
3. Wilson
4. Launchbury
5. Lawes
6. Croft -- There for the line-out and, hopefully, have a greater effect in a more attacking team.
7. Kvesic -- Hopefully takes to international rugby like a duck to water and moves Robshaw into the 6 shirt. Makes up for Croft standing on the wing.
8. Morgan
9. Care
10. Burns
11. May
12. Twelvetrees
13. Joseph -- Maybe Daly, but I think Joseph hasn't had a proper chance yet.
14. Wade
15. Brown
16. Gray/Buchanan
17. Doran-Jones/Knight/Thomas?
18. Vunipola/Marler -- Don't think Marler is as bad a scrummager as is being made out, but I haven't seen much of the loose work he's supposed to make up for it with.
19. Robson -- Choose the least bad, really. Don't rate any of the Saxons locks.
20. B. Vunipola -- Would like to see Fraser, but 8 is currently barren compared to all other positions.
21. Simpson -- Put an end to the aerial ping-pong against the Wolfhounds, starting the break that lead to the Fraser try.
22. Flood -- Ford not ready, option of experience should the youngsters in the backs lose their heads.
23. Eastmond -- Utility and class.
Add to that Catt having full rein in the backs and England should try and put another 60 points on the BaaBaas, and aim to score three or more in each game against Argentina. Cobble the remains to play the midweek games however you want.