I fear an Exeter win here.
They're a strong team, especially at home, and they're pretty much at full strength, whereas Sale are missing almost half of their starting XV (Sheridan, Gaskell, Seymour, Hodgson, Peel, Cueto, Williams - also some of the replacements, notably Tom Brady) either through injury or international duty (though some of the young guns coming through did look impressive in the LV= cup)