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Edinburgh v Glasgow</div>
Edinburgh welcome back Ross Ford, Gavin Kerr, Ross Rennie and John Houston for the visit of Glasgow to Murrayfield.
Houston replaces injured winger Mark Robertson, while full-back Chris Paterson still has a rib problem.
Glasgow captain Alastair Kellock is back and hooker Dougie Hall is reinstated after concussion.
Centre Graeme Morrison has recovered from a knee injury and, with Lome Fa'atau suffering a fractured shinbone, Hefin O'Hare moves to the right wing.
Thom Evans lines up on the left wing for the visitors, while prop Ed Kalman is given the nod ahead of Moray Low.
For the home side, Hugo Southwell continues to deputise for Paterson, as Houston and Kerr both make just their second starts of the season.
Glasgow sit third in the Magners League table, just six points behind leaders Munster.
Edinburgh trail in seventh place after seven matches but are only four points behind their Scottish rivals.
The match also serves as the first leg of the 1872 Challenge Cup, which is played for between the sides each year.
"Edinburgh are a quality team with a lot of heads-up rugby players," said Warriors head coach Sean Lineen, who will be defending the trophy.
"The Boxing Day game is going to be very exciting and full of movement."
A large crowd is expected at the home of Scottish rugby and Edinburgh skipper Mike Blair is looking forward to the occasion.
"Everyone is excited about the prospect of playing in front of a record crowd for an Edinburgh game," said the Scotland scrum-half.
"Derbies always create a special atmosphere and this match should prove to be a memorable event; the perfect way to finish 2008.
"Obviously last season we didn't manage to win the 1872 Cup, so we will be determined to bring the trophy back to Edinburgh this time around."
Edinburgh's Geoff Cross will face a late fitness test on an ankle knock to determine whether or not he will be named amongst the replacements.
Edinburgh: Hugo Southwell, John Houston, Ben Cairns, Nick De Luca, Simon Webster, Phil Godman, Mike Blair (capt), Allan Jacobsen, Ross Ford, Gavin Kerr, Craig Hamilton, Jim Hamilton, Scott Newlands, Ross Rennie, Allister Hogg.
Replacements: Andrew Kelly, Geoff Cross/Kyle Traynor, Matt Mustchin, Alan MacDonald, Greig Laidlaw, David Blair, Jim Thompson.
Glasgow Warriors: Bernardo Stortoni, Hefin O'Hare, Max Evans, Graeme Morrison, Thom Evans, Dan Parks, Colin Gregor, Justin Va'a, Dougie Hall, Ed Kalman, Tim Barker, Alastair Kellock (capt), Kelly Brown, John Barclay, Johnnie Beattie.
Replacements: Fergus Thomson, Moray Low, Dan Turner, Richie Vernon, Sam Pinder, Andrew Henderson, Ruaridh Jackson.
From BBC Sport
Edinburgh v Glasgow</div>
Edinburgh welcome back Ross Ford, Gavin Kerr, Ross Rennie and John Houston for the visit of Glasgow to Murrayfield.
Houston replaces injured winger Mark Robertson, while full-back Chris Paterson still has a rib problem.
Glasgow captain Alastair Kellock is back and hooker Dougie Hall is reinstated after concussion.
Centre Graeme Morrison has recovered from a knee injury and, with Lome Fa'atau suffering a fractured shinbone, Hefin O'Hare moves to the right wing.
Thom Evans lines up on the left wing for the visitors, while prop Ed Kalman is given the nod ahead of Moray Low.
For the home side, Hugo Southwell continues to deputise for Paterson, as Houston and Kerr both make just their second starts of the season.
Glasgow sit third in the Magners League table, just six points behind leaders Munster.
Edinburgh trail in seventh place after seven matches but are only four points behind their Scottish rivals.
The match also serves as the first leg of the 1872 Challenge Cup, which is played for between the sides each year.
"Edinburgh are a quality team with a lot of heads-up rugby players," said Warriors head coach Sean Lineen, who will be defending the trophy.
"The Boxing Day game is going to be very exciting and full of movement."
A large crowd is expected at the home of Scottish rugby and Edinburgh skipper Mike Blair is looking forward to the occasion.
"Everyone is excited about the prospect of playing in front of a record crowd for an Edinburgh game," said the Scotland scrum-half.
"Derbies always create a special atmosphere and this match should prove to be a memorable event; the perfect way to finish 2008.
"Obviously last season we didn't manage to win the 1872 Cup, so we will be determined to bring the trophy back to Edinburgh this time around."
Edinburgh's Geoff Cross will face a late fitness test on an ankle knock to determine whether or not he will be named amongst the replacements.
Edinburgh: Hugo Southwell, John Houston, Ben Cairns, Nick De Luca, Simon Webster, Phil Godman, Mike Blair (capt), Allan Jacobsen, Ross Ford, Gavin Kerr, Craig Hamilton, Jim Hamilton, Scott Newlands, Ross Rennie, Allister Hogg.
Replacements: Andrew Kelly, Geoff Cross/Kyle Traynor, Matt Mustchin, Alan MacDonald, Greig Laidlaw, David Blair, Jim Thompson.
Glasgow Warriors: Bernardo Stortoni, Hefin O'Hare, Max Evans, Graeme Morrison, Thom Evans, Dan Parks, Colin Gregor, Justin Va'a, Dougie Hall, Ed Kalman, Tim Barker, Alastair Kellock (capt), Kelly Brown, John Barclay, Johnnie Beattie.
Replacements: Fergus Thomson, Moray Low, Dan Turner, Richie Vernon, Sam Pinder, Andrew Henderson, Ruaridh Jackson.
From BBC Sport