Ideally I'd want England to start as they had been doing prior to Coronavirus and blasting out the blocks early and scoring a try in the first few mins. If we can get a smallish lead to start with then the Italians will need to force the game. When it comes to who you play when it's the whipping boys, there is little way to justify 1 selection over another. As the Italian fitness was poor at the best of times and likely even worse now, I think England should focus on power players to start the game and play a game play around keeping possession with the aim of tiring the Italians as quickly as possible and then switching to quicker and more dynamic players for the last quarter to try to rack up a score.